INTERNATIONAL INSTITUTE
OF BIOPHYSICS
Conference
on Biophotons 1999
Abstracts of the Conference Reports in
alphabetic Order
ULTRAWEAK PHOTON EMISSION IN DIFFERENTIATED FIBROBLASTS
Hugo J. Niggli
BioFoton AG, Rte. d'Essert , CH-1733 Treyvaux (FR) Switzerland (P.O.
Box 28, CH-1731 Ependes) Phone/Fax: 0041-264131445 E-mail: biofoton@mail.swissonline.ch
Photons participate in many atomic and molecular interactions and changes.
Recent biophysical research has shown the existence of ultraweak photons
in biological tissue. It is now established that plants, animal and human
cells emit a very weak radiation which can be readily detected with an
appropriate photomultiplier system. Although the emission is extremely
low in mammalian cells, it can be efficiently induced by ultraviolet light.
It was recently reported that UV-light elevates ultraweak photon emission
at least by a factor of 2 in mitomycin C (MMC)-induced postmitotic Xeroderma
pigmentosum (XP)-fibroblasts, the final stage of the fibroblast ageing
system described by Bayreuther and co-workers, compared to mitotic XP-cells.
All of these results confirm the highly interesting biophoton model published
in 1983 by Nagl and Popp which suggests that there is a negative feedback
loop in living cells which couples states of a coherent ultraweak photon
field with the conformational state of cellular DNA. They postulate photon
transfer from the cytoplasmic metabolism to the DNA which results in changes
of DNA conformation via excimer formation. Since the conformation of the
DNA molecule is believed to be of importance for the regulation of nuclear
information transfer, such processes in turn influence the metabolic activity
of the cell. Ultraweak photons are measured in the visible and the UV-range.
Photons in the visible range are coupled with radical reactions induced
by oxidant stress while photons in the UV are linked with the DNA as the
source. Preliminary experiments following UV-light irradiation show significant
ultraweak photon emission changes in distinct differentiation stages of
the fibroblast system and therefore, the sources and the mechanisms of
this very weak photon emission was investigated using the distinct differentiating
stages of fibroblasts. It was found, that ultraweak photons serve as excellent
tools in the fibroblast differentiation system to unravel further aging
and cancer mechanisms of human skin.
© International
Institute of Biophysics 2001 E-mail: iib@lifescientists.de