INTERNATIONAL INSTITUTE OF BIOPHYSICS
Conference on Biophotons 1999
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COHERENT PHENOMENA IN METABOLIC ORGANIZATION AND MORPHOGENESIS

A.U.Igamberdiev

Department of Plant Physiology and Biochemistry, Voronezh University, 394693, Voronezh, Russia

The concept of coherence as an organizing principle of biological structures was introduced by A.G.Gurwitsch  who formulated the idea of a low-energy field determining the continuous operation of a biosystem as a total entity. Coherent states actually bridge the gap between micro and macroscales, realizing the "prehension" (A.N.Whitehead) of single points into total entities. Interaction between the high-energy (based on the dynamic coherent non-equilibrium energy-driven processes) and the low-energy constraints (based on coherent quantum phenomena) underlies biological organization. Coherent energy transfer allows for macromolecules to operate with high efficiency and realize computation. The quantum coherent state is characterized by the minimum uncertainty condition, allowing for the provision of computation and information transfer with almost 100% efficiency. The information based on specific recognitions triggering dynamical energy-driven processes appears as non-digital (templating); the transfer of digital information is realized within hypercycles and corresponds to the encoding phenomenon. Templating (non-digital information) results from quantum arrangement of organized states based on recognition (non-demolition measurement). Encoding (digital information) arises as embedding (Gdel numbering) within the set of templates and underlies computation, i.e., encoding appears within reflective loops of templating. Optimality of living states is realized on the interface between digital and non-digital phenomena. The recognition process is a quantum measurement underlying the enzymatic conversion of a substrate into the product. The switching via separation of thedirect and reverse routes in futile cycles provides the generation and complication of metabolic networks, and the coherence within cycles is maintained by the supramolecular organization of enzymes. The genetic level corresponding to the appearance of digital information is based on reflective arrows (catalysts realize their own self-reproduction). Via coherent events percolating from the submolecular level to organismic entities self-assembly based on the molecular complementarity is realized and the dynamic morphogenetic field is generated. Functional activity of biosystems emerges during the process of morphogenesis via non-programmable generation of computable events through the coherent phenomena.
 

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