Institute of Biophysics, Academia Sinica, Beijing, China - Basic Research: Cellular Biophysics


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INTERNATIONAL INSTITUTE OF BIOPHYSICS

Basic Research-Cellular Biophysics
Institute of Biophysics, Academia Sinica, Beijing, China

Institute of Biophysics

Cellular Biophysics

Biophoton Emission

Applied Science

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Cellular Biophysics

cell communication

(1) Bioinformational effects of physical factors on living cells

It has been shown that some integral proteins of cell membranes like Na,K-ATPase can be activated by pulsed electric field and some physical factors can be taken by living cells as informational signals which can cross cell membrane and transmit within the cells through cellular signaling pathways, like through second messenger cAMP and IP3 and Ca+ pathways. Some publications were made in this direction ( see list of publications ).

(2) Coherence of biophotons and biophotonic communication

By using the double chamber measuring system synchronous photon emission from sample A and sample B when can "see" each other by opening the shutter between the two sample chambers has been observed. The synchronism can not be explained simply in terms of physical light scattering but of an electromagnetic interaction that takes part in communication between the two samples.

By using the coincidence counting system( CCS), the following preliminary results were shown :

(A). Distribution of measured coincidences of sample A and sample B follows theoretical Posson distribution rather than geometrical one for both cases of the shutter opened and closed suggesting that they are random and mere coherent than caotic. However there are some differences between the case of the shutter opened and closed. All perturbations were shown to influence sensitively the Possonian distribution , resulting in some deviation. Under some disturbances the photon sources still can keep the Possonian distribution although with some deviation, but some perturbations can destroy the Possonian distribution. (1996 Conference of Neuss). (B). Some samples show that the measured coincidence deviates to a higher value than the random coincidence when the shutter opened whereas deviates to lower when the shutter closed. By changing measuring parameters, this phenomenon can become more identical.( 1997 Conference of Neuss). Major publications on this field: (1) Zhang,J.Z.,Yu,W.D., Sun,T. and F.A. Popp(1997): Spontaneous and light-induced photon emission from intact brains of chick embryos, Science in China ( Series C) 40(1), 44-51

(2) Zhang Jinzhu, Sun tong, Chen Ya, Zhou Shuhua, Chen Yunjun and Pang Su zhen (1997): Studies on Changed of Intracellular Na+ Concentration in Erythrocytes Effected by Pulsed Electrical Field, Science in China( Series C )( in press)

(3) Shen,H.H. and J.J. Chang: Effects of pulsed electric field on cytosolic Ca2+ and cAMP levels in embryonic chick brain cells, Acta Biophys. Sinica. 1997(1),(in Chinese with English abstract)

(4) Chang,J.J .,F.A.Popp, and W.D.Yu (1995): Communication between Dinoflagellates by Means of Photon Emission. in " Proceedings of International Conference on Non-equilibrium and Coherent Systems in Biophysics, Biology and Biotechnology. Sep. 28-Oct.2. 1994, Moscow.eds,L.V. Beloussov and F.A. Popp, Bioinform Services Co. Russia, 1995,p318-330.

(5) Yu,W.Dwazzu .,J.J.Chang,(1995): Studies on the Development of Embryonic Chicken Brain Cells by means of Photon Emission, Chinese Science Bulletin,40:1317-1321

(6) Zhang,J.Z.,F.A.Popp, and W.D.Yu,(1995): Research on Cell Communication of P.elegans by Means of Photon Emission. Chines Science Bulletin. 40:76-79

(7) Chang,J.J.,Y.Liu.,and K.J.Kong,(1994): Dynamic Cell Membrane Events Following the Application of Single Pulse Electric Field. in " Bioelectrodynamics and Biocommunication" (ed.Hothey ,M.W.,F.A.Popp and U.Warnke) Word Scientific Publishing Co. 251-268

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